Endothelial function in patients with familial Mediterranean fever-related amyloidosis and association with cardiovascular events

Yilmaz, Mahmut; Demirkaya, Erkan; Acikel, Cengizhan; Saldir, Mehmet; Akar, Servet; Cayci, Tuncer; Saglam, Mutlu; Unal, Hilmi; Gok, Mahmut; Polat, Adem; Cetinkaya, Hakki; Eyileten, Tayfun; Sari, Sebahattin; Yildirim, Ali; Sonmez, Alper; Oguz, Yusuf; Vural, Abdulgaffar; ÖZEN, SEZA; Carrero, Juan

doi:10.1093/rheumatology/keu231

Endothelial function in patients with familial Mediterranean fever-related amyloidosis and association with cardiovascular events

Yilmaz M. I., Demirkaya E., Acikel C., Saldir M., Akar S., Cayci T., ...More

RHEUMATOLOGY, vol.53, no.11, pp.2002-2008, 2014 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 53 Issue: 11
Publication Date: 2014
Doi Number: 10.1093/rheumatology/keu231
Journal Name: RHEUMATOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.2002-2008
Open Archive Collection: AVESIS Open Access Collection
Hacettepe University Affiliated: Yes

Abstract

Objectives. Secondary amyloidosis is the most important complication of FMF and endothelial function is more severely impaired. Elevated asymmetric dimethyl arginine (ADMA) may mediate the excess cardiovascular disease (CVD) risk of this group. We aimed to compare endothelial function characteristics, including ADMA, in patients with FMF-related amyloidosis and primary glomerulopathies and to define risk factors for a CVD event.