Endothelial function in patients with familial Mediterranean fever-related amyloidosis and association with cardiovascular events

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Yilmaz M. I., Demirkaya E., Acikel C., Saldir M., Akar S., Cayci T., ...More

RHEUMATOLOGY, vol.53, no.11, pp.2002-2008, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 11
  • Publication Date: 2014
  • Doi Number: 10.1093/rheumatology/keu231
  • Journal Name: RHEUMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2002-2008
  • Hacettepe University Affiliated: Yes

Abstract

Objectives. Secondary amyloidosis is the most important complication of FMF and endothelial function is more severely impaired. Elevated asymmetric dimethyl arginine (ADMA) may mediate the excess cardiovascular disease (CVD) risk of this group. We aimed to compare endothelial function characteristics, including ADMA, in patients with FMF-related amyloidosis and primary glomerulopathies and to define risk factors for a CVD event.