Thermolabile methylenetetrahydrofolate reductase enzyme genotype is frequent in type 2 diabetic patients with normal fasting homocysteine levels

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Tutuncu N., Erbas T., Alikasifoglu M., Tuncbilek E.

JOURNAL OF INTERNAL MEDICINE, vol.257, no.5, pp.446-453, 2005 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 257 Issue: 5
• Publication Date: 2005
• Doi Number: 10.1111/j.1365-2796.2005.01480.x
• Journal Name: JOURNAL OF INTERNAL MEDICINE
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.446-453
• Hacettepe University Affiliated: Yes

Abstract

Objective. To investigate the plasma homocysteine concentrations with regard to nutritional, metabolic and genetic factors and to find out the frequency and impact of thermolabile methylenetetrahydrofolate reductase (T-MTHFR) polymorphism in patients with type 2 diabetes mellitus.