Analysis of MTHFR 1298A > C in addition to MTHFR 677C > T polymorphism as a risk factor for neural tube defects in the Turkish population

BODUROĞLU O. K., ALANAY Y., Alikasifoglu M., Aktas D., Tuncbilek E.

TURKISH JOURNAL OF PEDIATRICS, cilt.47, sa.4, ss.327-333, 2005 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 4
  • Basım Tarihi: 2005
  • Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.327-333
  • Anahtar Kelimeler: methylenetetrahydrofolate reductase, MTHFR, neural tube defects, polymorphism, MTHFR 677C > T polymorphism, MTHFR 1298A > C polymorphism, METHYLENETETRAHYDROFOLATE REDUCTASE GENE, 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE, SPINA-BIFIDA, PLASMA HOMOCYSTEINE, COMMON MUTATION, C677T MUTATION, FOLATE, ASSOCIATION, GENOTYPES, SUSCEPTIBILITY
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Maternal folic acid intake in the periconceptional period is strongly related to reduction in recurrence and occurrence of birth defects involving the neural tube.