Interleukin-10 gene transfer: Prevention of multiple organ injury in a murine cecal ligation and puncture model of sepsis

KABAY, YUSUF; Kocaefe, Cetin; Baykal, ATAÇ; OEZDEN, Hilmi; BAYCU, Cengiz; ONER, Zafer; Oezguec, Meral; SAYEK, Iskender

doi:10.1007/s00268-006-0066-9

Interleukin-10 gene transfer: Prevention of multiple organ injury in a murine cecal ligation and puncture model of sepsis

KABAY B., Kocaefe C., Baykal A., OEZDEN H., BAYCU C., ONER Z., ...Daha Fazla

WORLD JOURNAL OF SURGERY, cilt.31, sa.1, ss.105-115, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 31 Sayı: 1
Basım Tarihi: 2007
Doi Numarası: 10.1007/s00268-006-0066-9
Dergi Adı: WORLD JOURNAL OF SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.105-115
Hacettepe Üniversitesi Adresli: Evet

Özet

Introduction: The aim of this study was to determine the effect of immunoregulatory cytokine interleukin-10 (IL-10) gene therapy on multiple organ injury (MOI) induced by a cecal ligation and puncture (CLP) model of sepsis in mice.