Comparative effects of methylprednisolone and tetracosactide (ACTH(1-24)) on ischemia/reperfusion injury of the rabbit spinal cord

Kertmen, Hayri; Celikoglu, Erhan; Ozturk, Ozden; Gurer, Bora; BOZKURT, HÜSEYİN; Kanat, Mehmet; Arikok, Ata; ERGÜDER, BERRİN; SARGON, MUSTAFA; Sekerci, Zeki

doi:10.5114/aoms.2017.65650

Comparative effects of methylprednisolone and tetracosactide (ACTH(1-24)) on ischemia/reperfusion injury of the rabbit spinal cord

Kertmen H., Celikoglu E., Ozturk O. C., Gurer B., BOZKURT H., Kanat M. A., ...Daha Fazla

ARCHIVES OF MEDICAL SCIENCE, cilt.14, sa.6, ss.1459-1470, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 14 Sayı: 6
Basım Tarihi: 2018
Doi Numarası: 10.5114/aoms.2017.65650
Dergi Adı: ARCHIVES OF MEDICAL SCIENCE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1459-1470
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Hacettepe Üniversitesi Adresli: Evet

Özet

Introduction: Tetracosactide is an engineered peptide that applies the same biological impacts as the endogenous adrenocorticotropic hormone. Previous studies indicated that tetracosactide has anti-inflammatory, antioxidant and neurotrophic activity. In this study, we hypothesized that tetracosactide may have protective effects in spinal cord ischemia-reperfusion injury.