In silico validation of the Autoinflammatory Disease Damage Index


ter Haar N. M. , van Delft A. L. J. , Annink K. V. , van Stel H., Al-Mayouf S. M. , Amaryan G., ...More

ANNALS OF THE RHEUMATIC DISEASES, vol.77, no.11, pp.1599-1605, 2018 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 77 Issue: 11
  • Publication Date: 2018
  • Doi Number: 10.1136/annrheumdis-2018-213725
  • Journal Name: ANNALS OF THE RHEUMATIC DISEASES
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1599-1605

Abstract

Introduction Autoinflammatory diseases can cause irreversible tissue damage due to systemic inflammation. Recently, the Autoinflammatory Disease Damage Index (ADDI) was developed. The ADDI is the first instrument to quantify damage in familial Mediterranean fever, cryopyrin-associated periodic syndromes, mevalonate kinase deficiency and tumour necrosis factor receptor-associated periodic syndrome. The aim of this study was to validate this tool for its intended use in a clinical/research setting.