Evaluation of the Neurotoxicity of the Polyethylene Glycol Hydrogel Dural Sealant

BAKAR B., Kose E. A., Balci M., Atasoy P., Sarkarati B., ALHAN A., ...More

TURKISH NEUROSURGERY, vol.23, no.1, pp.16-24, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.5137/1019-5149jtn.6039-12.1
  • Journal Name: TURKISH NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.16-24
  • Hacettepe University Affiliated: Yes

Abstract

AIM: Although polyethylene glycol (PEG) is a neutral, biocompatible hydrophilic polymer recognized for its lack of interaction with biological barrier, its neurotoxicity has not been clearly identified in neurosurgery. This study is constructed to evaluate the possible neurotoxicity of a PEG hydrogel dural sealant.