Modeling the spreading cortical depression wavefront
VISUALIZATION AND IMAGING IN TRANSPORT PHENOMENA, cilt.972, ss.127-132, 2002 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 972
- Basım Tarihi: 2002
- Doi Numarası: 10.1111/j.1749-6632.2002.tb04562.x
- Dergi Adı: VISUALIZATION AND IMAGING IN TRANSPORT PHENOMENA
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.127-132
- Hacettepe Üniversitesi Adresli: Hayır
Özet
Spreading cortical depression (SCD) is a wave of depolarization that spreads across the cortex at 2-5 mm/min and is followed by a 5-10 minute reduction in EEG activity. It is assumed that SCD is involved in the pathophysiology of migraine. We present a new model and a visualization technique for the spread of excitation on realistic brain surfaces. The usefulness of the technique is demonstrated on a rat brain that had been segmented from a three-dimensional magnetic resonance image data set. With the help of this methodology it is possible to create specific patient models to better understand the mechanisms of SCD.