Extraovarian juvenile granulosa cell tumor in a prepubertal child: novel location of a rare tumor

USER İ. R., ARDIÇLI B., YALÇIN B., ORHAN D., MÜNGEN E., ozcan N., ...More

PEDIATRIC HEMATOLOGY AND ONCOLOGY, vol.38, no.3, pp.272-277, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.1080/08880018.2020.1850953
  • Journal Name: PEDIATRIC HEMATOLOGY AND ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE
  • Page Numbers: pp.272-277
  • Keywords: Child, extragonadal, Juvenile granulosa cell tumor
  • Hacettepe University Affiliated: Yes

Abstract

Juvenile granulosa cell tumor (JGCT) is the most common type of sex cord stromal tumor arising from gonadal structures of children and young adults. We present a 3.5-year-old girl with JGCT located in retroperitoneum without ovarian involvement. Extragonadal occurrences of other sex cord stromal tumors have been rarely reported, but this is the first case of JGCT in an extragonadal location. We speculate the possible underlying mechanism of sex cord stromal tumor formation in extragonadal locations. Furthermore, clinical presentation, differential diagnosis and management of this tumor in childhood are discussed.