Urethanes synthesis from oxamic acids under electrochemical conditions

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Ogbu I. M., Lusseau J., Kurtay G., Robert F., Landais Y.

Chemical Communications, vol.56, no.81, pp.12226-12229, 2020 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 81
  • Publication Date: 2020
  • Doi Number: 10.1039/d0cc05069e
  • Journal Name: Chemical Communications
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chimica, Communication Abstracts, EMBASE, MEDLINE, DIALNET
  • Page Numbers: pp.12226-12229
  • Hacettepe University Affiliated: No

Abstract

© The Royal Society of Chemistry.Urethane synthesis via oxidative decarboxylation of oxamic acids under mild electrochemical conditions is reported. This simple phosgene-free route to urethanes involves an in situ generation of isocyanates by anodic oxidation of oxamic acids in an alcoholic medium. The reaction is applicable to a wide range of oxamic acids, including chiral ones, and alcohols furnishing the desired urethanes in a one-pot process without the use of a chemical oxidant.