Urethanes synthesis from oxamic acids under electrochemical conditions
Chemical Communications, vol.56, no.81, pp.12226-12229, 2020 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 56 Issue: 81
- Publication Date: 2020
- Doi Number: 10.1039/d0cc05069e
- Journal Name: Chemical Communications
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chimica, Communication Abstracts, EMBASE, MEDLINE, DIALNET
- Page Numbers: pp.12226-12229
- Open Archive Collection: AVESIS Open Access Collection
- Hacettepe University Affiliated: No
Abstract
© The Royal Society of Chemistry.Urethane synthesis via oxidative decarboxylation of oxamic acids under mild electrochemical conditions is reported. This simple phosgene-free route to urethanes involves an in situ generation of isocyanates by anodic oxidation of oxamic acids in an alcoholic medium. The reaction is applicable to a wide range of oxamic acids, including chiral ones, and alcohols furnishing the desired urethanes in a one-pot process without the use of a chemical oxidant.