Lens concentration of ofloxacin and lomefloxacin in an experimental endophthalmitis model

Yagci, Ramazan; Oflu, Yusuf; Yagci, Server; Dincel, Aysun; Kaya, Esma; Duman, Sunay; Bozkurt, ATİLLA

doi:10.1016/j.curtheres.2007.06.003

Lens concentration of ofloxacin and lomefloxacin in an experimental endophthalmitis model

Atıf İçin Kopyala

Yagci R., Oflu Y., Yagci S., Dincel A., Kaya E., Duman S., ...Daha Fazla

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, cilt.68, sa.3, ss.184-190, 2007 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 68 Sayı: 3
Basım Tarihi: 2007
Doi Numarası: 10.1016/j.curtheres.2007.06.003
Dergi Adı: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.184-190
Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Bacterial endophthalmitis is a serious complication of ocular surgery and penetrating trauma. The primary causative organisms are strains of Staphylococcus aureus and Staphylococcus epidermidis. Fluoroquinolones are widely used to treat endophthalmitis. There are a few studies on the penetration of fluoroquinolones into the lens in inflamed eyes. A literature search did not identify any data regarding penetration of topical ofloxacin into the lens in normal and inflamed eyes.