Lens concentration of ofloxacin and lomefloxacin in an experimental endophthalmitis model


Yagci R., Oflu Y., Yagci S., Dincel A., Kaya E., Duman S., ...Daha Fazla

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, cilt.68, ss.184-190, 2007 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 68 Konu: 3
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.curtheres.2007.06.003
  • Dergi Adı: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
  • Sayfa Sayıları: ss.184-190

Özet

Background: Bacterial endophthalmitis is a serious complication of ocular surgery and penetrating trauma. The primary causative organisms are strains of Staphylococcus aureus and Staphylococcus epidermidis. Fluoroquinolones are widely used to treat endophthalmitis. There are a few studies on the penetration of fluoroquinolones into the lens in inflamed eyes. A literature search did not identify any data regarding penetration of topical ofloxacin into the lens in normal and inflamed eyes.