Light and Electron Microscopic Examination of Exocrine Pancreas Using Zinc Iodide-Osmium Tetroxide Technique
Okajimas Folia Anatomica Japonica, vol.75, no.5, pp.247-250, 1998 (Scopus)
- Publication Type: Article / Article
- Volume: 75 Issue: 5
- Publication Date: 1998
- Doi Number: 10.2535/ofaj1936.75.5_247
- Journal Name: Okajimas Folia Anatomica Japonica
- Journal Indexes: Scopus, BIOSIS, MEDLINE
- Page Numbers: pp.247-250
- Open Archive Collection: AVESIS Open Access Collection
- Hacettepe University Affiliated: Yes
Abstract
Zinc iodide-osmium tetroxide (ZIO) fixation/staining technique is a metallophilic technique which has been used for the examination of various tissues and cell types. We examined the ZIO (+) cell types in rat exocrine pancreas to obtain further evidence for the significance of the reaction. Among mostly non-reactive pancreatic acinar cells there were ZIO (+) acinar cells of varying staining intensity. Zymogenic granules and centroacinar cells were completely non-reactive. Our electron microscopic findings support the view that the reactivity of the technique used is cell specific but not cell type or organelle specific.