Comparative dural closure techniques: a safety study in rats

OZİSİK P. A., Inci S., SOYLEMEZOGLU F., ORHAN H., ÖZGEN T.

SURGICAL NEUROLOGY, vol.65, no.1, pp.42-47, 2006 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 65 Issue: 1
  • Publication Date: 2006
  • Doi Number: 10.1016/j.surneu.2005.04.047
  • Journal Name: SURGICAL NEUROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.42-47
  • Hacettepe University Affiliated: Yes

Abstract

Background: Some neurosurgical procedures have high morbidity and mortality rates due to cerebrospinal fluid (CSF) fistula development, particularly when dural defects are in relatively inaccessible areas or surrounded by friable dura. We used a rat model to test 4 different dural closure techniques to determine which one was significantly superior for achieving a watertight dural closure with minimal harm to brain tissue.