The effect of colchicine and low-dose methotrexate on intestinal ischemia/reperfusion injury in an experimental model

Boybeyi Ö., Gunal Y. D., Atasoy P., Kisa U., Aslan M. K.

JOURNAL OF PEDIATRIC SURGERY, vol.49, no.10, pp.1471-1474, 2014 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 49 Issue: 10
  • Publication Date: 2014
  • Doi Number: 10.1016/j.jpedsurg.2014.01.057
  • Journal Name: JOURNAL OF PEDIATRIC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1471-1474
  • Keywords: Intestinal ischemia, Ischemia/reperfusion injury, Colchicine, Methotrexate, Experimental, RATS, ISCHEMIA
  • Hacettepe University Affiliated: No

Abstract

Aim: Intestinal ischemia/reperfusion (I/R) injury is a serious clinical condition. Colchicine and low-dose methotrexate have anti-inflammatory features. An experimental model was conducted to investigate the effect of colchicine and methotrexate on intestinal I/R injury.