The effect of colchicine and low-dose methotrexate on intestinal ischemia/reperfusion injury in an experimental model

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Boybeyi Ö., Gunal Y. D., Atasoy P., Kisa U., Aslan M. K.

JOURNAL OF PEDIATRIC SURGERY, vol.49, no.10, pp.1471-1474, 2014 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 49 Issue: 10
• Publication Date: 2014
• Doi Number: 10.1016/j.jpedsurg.2014.01.057
• Journal Name: JOURNAL OF PEDIATRIC SURGERY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1471-1474
• Keywords: Intestinal ischemia, Ischemia/reperfusion injury, Colchicine, Methotrexate, Experimental, RATS, ISCHEMIA
• Hacettepe University Affiliated: No

Abstract

Aim: Intestinal ischemia/reperfusion (I/R) injury is a serious clinical condition. Colchicine and low-dose methotrexate have anti-inflammatory features. An experimental model was conducted to investigate the effect of colchicine and methotrexate on intestinal I/R injury.