The effect of colchicine and low-dose methotrexate on intestinal ischemia/reperfusion injury in an experimental model

Boybeyi, ÖZLEM; Gunal, Yasemin; Atasoy, Pinar; Kisa, Ucler; Aslan, Mustafa

doi:10.1016/j.jpedsurg.2014.01.057

The effect of colchicine and low-dose methotrexate on intestinal ischemia/reperfusion injury in an experimental model

Boybeyi Ö., Gunal Y. D., Atasoy P., Kisa U., Aslan M. K.

JOURNAL OF PEDIATRIC SURGERY, cilt.49, sa.10, ss.1471-1474, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 49 Sayı: 10
Basım Tarihi: 2014
Doi Numarası: 10.1016/j.jpedsurg.2014.01.057
Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1471-1474
Anahtar Kelimeler: Intestinal ischemia, Ischemia/reperfusion injury, Colchicine, Methotrexate, Experimental, RATS, ISCHEMIA
Hacettepe Üniversitesi Adresli: Hayır

Özet

Aim: Intestinal ischemia/reperfusion (I/R) injury is a serious clinical condition. Colchicine and low-dose methotrexate have anti-inflammatory features. An experimental model was conducted to investigate the effect of colchicine and methotrexate on intestinal I/R injury.