Effect of inflammation on cytokine levels and bone remodelling markers in peri-implant sulcus fluid: A preliminary report

GÜNCÜ G. N. , AKMAN A. C. , Gunday S., YAMALIK N. , BERKER E.

CYTOKINE, vol.59, no.2, pp.313-316, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1016/j.cyto.2012.04.024
  • Title of Journal : CYTOKINE
  • Page Numbers: pp.313-316

Abstract

Objectives: Since ingredients of pen-implant sulcus fluid (PISF) may be related to the bony structure surrounding dental implants, analyze of specific markers related to bone resorption in PISF seems to be suitable for long term monitoring of pen-implant health. It is suggested that analysis of PISF may serve for detection of inflammation. The aim of this study is to analyze PISF interleukin-1 beta (IL-1 beta), IL-10, osteoprotegerin (OPG), receptor activator of nuclear factor-kappa B ligand (RANKL) levels to determine whether the diagnostic value of PISF can be used to evaluate early changes around implants.