Recurrent Salmonella bacteremia in interleukin-12 receptor beta 1 deficiency


Ozen M., Ceyhan M. , Sanal O., Bayraktar M., Mesci L.

JOURNAL OF TROPICAL PEDIATRICS, vol.52, no.4, pp.296-298, 2006 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 4
  • Publication Date: 2006
  • Doi Number: 10.1093/tropej/fml001
  • Title of Journal : JOURNAL OF TROPICAL PEDIATRICS
  • Page Numbers: pp.296-298

Abstract

Interleukin-12 receptor beta 1 (IL12RB1) deficiency causes vulnerability to poorly virulent mycobacteria and nontyphoid Salmonella species. We describe a 2.5 year-old girl with IL12RB1 deficiency, caused by a homozygous; mutation in this gene, who presented with recurrent bacteremia caused by Salmonella spp.