Lithium-associated hypothyroidism and thyroid papillary carcinoma: A case report

Aksoy S., Kilickap S., Erman M.

SOUTHERN MEDICAL JOURNAL, vol.99, no.3, pp.279-281, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 99 Issue: 3
  • Publication Date: 2006
  • Doi Number: 10.1097/01.smj.0000203332.70689.b6
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.279-281
  • Hacettepe University Affiliated: Yes


Ionizing radiation, some hereditary factors, and chronic thyroid-stimulating hormone elevation increases the risk of differentiated thyroid carcinoma. Lithium salts are used in the treatment of affective (mood) disorders as well as a variety of other psychiatric conditions. There have been occasional reports of hematologic and solid neoplasms associated with lithium use. We report a patient who developed hypothyroidism and subsequently, thyroid papillary carcinoma while on lithium treatment for bipolar affective disorder.