Treatment in childhood central nervous system demyelinating disorders

KONUŞKAN B., Anlar B.

DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, cilt.61, sa.11, ss.1281-1289, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 61 Sayı: 11
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1111/dmcn.14228
  • Dergi Adı: DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1281-1289
  • Hacettepe Üniversitesi Adresli: Evet

Özet

The last two decades witnessed significant advances in the treatment of acquired demyelinating disorders: thirteen new agents have been approved for the treatment of multiple sclerosis in adults by the European Medicines Agency and US Food and Drug Administration in the last twenty years. Although the long-term efficacy and safety profiles of some new drugs are still being assessed in paediatric MS, clinicians may have to use them in the management of paediatric onset MS resistant to first-line medications, based on results obtained in adult-onset disease. This review summarizes the current approach to treatment in children with demyelinating syndromes. What this paper adds