Raising the bar to ultradisciplinary collaborations in management of chronic thromboembolic pulmonary hypertension

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Akay T., Kaymaz C., AKAR A. R., Orhan G., Yanartas M., Gultekin B., ...Daha Fazla

TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, cilt.29, sa.3, ss.417-431, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 29 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5606/tgkdc.dergisi.2021.21284
  • Dergi Adı: TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.417-431
  • Anahtar Kelimeler: Balloon pulmonary angioplasty, chronic thromboembolic pulmonary hypertension, pulmonary endarterectomy, pulmonary thromboembolism, targeted medical therapy, RISK-FACTORS, NATRIURETIC PEPTIDE, ENDARTERECTOMY, ANGIOPLASTY, RIOCIGUAT, OUTCOMES, DISEASE, THROMBOENDARTERECTOMY, PERFUSION, SURVIVAL
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Chronic thromboembolic pulmonary hypertension is an underdiagnosed and potentially fatal subgroup of pulmonary hypertension, if left untreated. Clinical signs include exertional dyspnea and non-specific symptoms. Diagnosis requires multimodality imaging and heart catheterization. Pulmonary endarterectomy, an open heart surgery, is the gold standard treatment of choice in selected patients in specialized centers. Targeted medical therapy and balloon pulmonary angioplasty can be effective in high-risk patients with significant comorbidities, distal pulmonary vascular obstructions, or recurrent/persistent pulmonary hypertension after pulmonary endarterectomy. Currently, there is a limited number of data regarding novel coronavirus-2019 infection in patients with chronic thromboembolic pulmonary hypertension and the changing spectrum of the disease during the pandemic. Challenging times during this outbreak due to healthcare crisis and relatively higher case-fatality rates require convergence; that is an ultradisciplinary collaboration, which crosses disciplinary and sectorial boundaries to develop integrated knowledge and new paradigms. Management strategies for the "new normal" such as virtual care, preparedness for further threats, redesigned standards and working conditions, reevaluation of specific recommendations, and online collaborations for optimal decisions for chronic thromboembolic pulmonary hypertension patients may change the poor outcomes.