In vivo behaviour of vesicular urokinase

Erdogan S., Ozer A. Y., Bilgili H.

INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol.295, pp.1-6, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 295
  • Publication Date: 2005
  • Doi Number: 10.1016/j.ijpharm.2005.01.021
  • Journal Name: INTERNATIONAL JOURNAL OF PHARMACEUTICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1-6
  • Keywords: thrombosis, urokinase, liposome, niosome, sphingosome, biodistribution studies, STREPTOKINASE, PHOSPHOLIPIDS
  • Hacettepe University Affiliated: Yes

Abstract

Thromboembolic diseases including deep vein thrombus (DVT) are major causes of morbidity and mortality. Detection of DVT in low extremities is difficult. There are some accepted imaging techniques in clinic but most of them have several disadvantages limiting their effective use. Because of this, researchers are still performed to develop a rapid, specific means of detecting and/or imaging venous thrombi-based on the changing composition of the thrombus.