Skin-Type Adnexal Tumor With Trichoblastic Germinative Differentiation in the Breast: A Case Report

GÖKÖZ Ö., Presenti L., Gambacorta G., Zolfanelli F., Tricarico R., Nistri R., ...More

INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, vol.19, no.4, pp.527-533, 2011 (SCI-Expanded) identifier identifier identifier


Adnexal tumors with follicular differentiation in the breast parenchyma are rarely encountered. The authors present a unique case arising in a 64-year-old woman, in whom they observed composite differentiation toward follicular germinative cells of the hair follicle with focal areas of outer root sheath differentiation and pilar-type keratinization. The histogenesis of this tumor is analyzed in light of the peculiar pathological, immunohistochemical, and molecular genetic findings.