Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Enterobacteriaceae other than Escherichia coli


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Schumacher A., Steinke P., Bohnert J., Akova M., Jonas D., Kern W.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, vol.57, no.2, pp.344-348, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 2
  • Publication Date: 2006
  • Doi Number: 10.1093/jac/dki446
  • Journal Name: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.344-348
  • Hacettepe University Affiliated: No

Abstract

Objectives: 1-(1-Naphthylmethyl)-piperazine (NMP) has been shown to reverse multidrug resistance (MDR) in Escherichia coli overexpressing RND type efflux pumps, but there is no data on its activity in Enterobacteriaceae other than E. coli.