Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Enterobacteriaceae other than Escherichia coli

Schumacher, A; Steinke, P; Bohnert, JA; Akova, M; Jonas, D; Kern, WV

doi:10.1093/jac/dki446

Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Enterobacteriaceae other than Escherichia coli

Atıf İçin Kopyala

Schumacher A., Steinke P., Bohnert J., Akova M., Jonas D., Kern W.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, cilt.57, ss.344-348, 2006 (SCI İndekslerine Giren Dergi)

Cilt numarası: 57 Konu: 2
Basım Tarihi: 2006
Doi Numarası: 10.1093/jac/dki446
Dergi Adı: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Sayfa Sayıları: ss.344-348

Özet

Objectives: 1-(1-Naphthylmethyl)-piperazine (NMP) has been shown to reverse multidrug resistance (MDR) in Escherichia coli overexpressing RND type efflux pumps, but there is no data on its activity in Enterobacteriaceae other than E. coli.