Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Enterobacteriaceae other than Escherichia coli


Schumacher A., Steinke P., Bohnert J., Akova M., Jonas D., Kern W.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, vol.57, no.2, pp.344-348, 2006 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 2
  • Publication Date: 2006
  • Doi Number: 10.1093/jac/dki446
  • Title of Journal : JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
  • Page Numbers: pp.344-348

Abstract

Objectives: 1-(1-Naphthylmethyl)-piperazine (NMP) has been shown to reverse multidrug resistance (MDR) in Escherichia coli overexpressing RND type efflux pumps, but there is no data on its activity in Enterobacteriaceae other than E. coli.