Comparison of the Toxicities of Ethylene Vinyl Alcohol Copolymer Preparations, Dimethyl Sulphoxide and N-Butyl 2-Cyanoacrylate on Cerebral Parenchyma in an Experimental Rabbit Model


Ozdol C., Turk C. C. , Hazer D. B. , Yildirim A. E. , ARAT A. , ATİLLA P. , ...More

TURKISH NEUROSURGERY, vol.25, no.3, pp.446-452, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 3
  • Publication Date: 2015
  • Doi Number: 10.5137/1019-5149.jtn.12592-14.1
  • Title of Journal : TURKISH NEUROSURGERY
  • Page Numbers: pp.446-452

Abstract

AIM: Ethylene vinyl alcohol copolymer (EVOH), its organic solvent dimethyl sulfoxide (DMSO), and N-Butyl 2-Cyanoacrylate (NBCA) are widely used in neurovascular embolization procedures and yet with potential risk of cytotoxicity.The aim of this study was to evaluate the toxic effect of EVOH-DMSO, its solvent DMSO and NBCA on cerebral parenchyma in a rabbit model.