Risk factors for linezolid-associated thrombocytopenia and negative effect of carbapenem combination


Kilic E. K. , Bulut C., SÖNMEZER M. Ç. , Ozel O., Hatipoglu C. A. , Ertem G. T. , ...More

JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, vol.13, no.10, pp.886-891, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 10
  • Publication Date: 2019
  • Doi Number: 10.3855/jidc.10859
  • Title of Journal : JOURNAL OF INFECTION IN DEVELOPING COUNTRIES
  • Page Numbers: pp.886-891

Abstract

Introduction: Linezolid is a synthetic antimicrobial agent with a broad spectrum of activity against virtually all Gram-positive bacteria. Although linezolid is generally well tolerated, the prolonged use of linezolid can lead to myelosuppression, including neutropenia, thrombocytopenia, and anemia. The aim of this study was investigating the risk factors for thrombocytopenia in patients who received linezolid therapy.