Effects of Work Place Carbon Monoxide Exposure on Blood Viscosity


Neslihan D. , Nurten S.

ARCHIVES OF ENVIRONMENTAL & OCCUPATIONAL HEALTH, cilt.65, ss.49-53, 2010 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 65 Konu: 1
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1080/19338240903392640
  • Dergi Adı: ARCHIVES OF ENVIRONMENTAL & OCCUPATIONAL HEALTH
  • Sayfa Sayıları: ss.49-53

Özet

Both blood viscosity and carbon monoxide (CO) has been associated with cardiovascular diseases (CVDs). In order to investigate the effects of chronic low-level CO exposure on the determinants of blood viscosity (hematocrit, plasma viscosity, erythrocyte deformability, and erythrocyte aggregation), 10 men exposed to CO at work for at least 6 months and 10 healthy controls were included in the study. Plasma viscosity was determined by a cone-plate viscometer, erythrocyte deformability and erythrocyte aggregation by laser-assisted optical rotational cell analyzer. Mean plasma viscosity of the group exposed to CO (1.4 +/- 0.1 mPa.sn) was significantly higher than that of the controls (1.2 +/- 0.06 mPa.sn) (p < .05). Plasma fibrinogen level of the CO group (275 +/- 11 mg/dL) was slightly higher than that of the controls (263 +/- 14 mg/dL). The rise in plasma viscosity by chronic low-level CO exposure may be the mechanism of CO-induced increase in the risk for CVDs.