Determination of Regional Intestinal Permeability of Diclofenac and Metoprolol Using a Newly-Developed and Validated High Performance Liquid Chromatographic Method

KAYNAK, MUSTAFA; Buyuktuncel, Ebru; ÇAĞLAR YILMAZ, HATİCE; ŞAHİN, SELMA

doi:10.4314/tjpr.v14i1.23

Determination of Regional Intestinal Permeability of Diclofenac and Metoprolol Using a Newly-Developed and Validated High Performance Liquid Chromatographic Method

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KAYNAK M. O., Buyuktuncel E., ÇAĞLAR YILMAZ H., ŞAHİN S.

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, vol.14, no.1, pp.163-170, 2015 (SCI-Expanded)

Publication Type: Article / Article
Volume: 14 Issue: 1
Publication Date: 2015
Doi Number: 10.4314/tjpr.v14i1.23
Journal Name: TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.163-170
Hacettepe University Affiliated: Yes

Abstract

Purpose: To develop a simple and rapid reversed-phase high performance liquid chromatographic (HPLC) method with UV detection for the simultaneous determination of diclofenac, metoprolol tartrate, phenol red and propyl paraben in intestinal segments.