Contractile apparatus in CNS capillary pericytes

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ERDENER Ş. E., Kureli G., DALKARA T.

NEUROPHOTONICS, vol.9, no.2, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 9 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.1117/1.nph.9.2.021904
  • Journal Name: NEUROPHOTONICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Compendex, EMBASE, INSPEC, Directory of Open Access Journals
  • Keywords: pericyte, actin, contractility, central nervous system, capillary, blood flow, VASCULAR SMOOTH-MUSCLE, RHO-ASSOCIATED KINASE, ACTIN CYTOSKELETON, BLOOD-FLOW, F-ACTIN, MICROVASCULAR PERICYTES, MESSENGER-RNA, BETA-ACTIN, POLYMERIZATION, PHALLOIDIN
  • Hacettepe University Affiliated: Yes

Abstract

Significance: Whether or not capillary pericytes contribute to blood flow regulation in the brain and retina has long been debated. This was partly caused by failure of detecting the contractile protein alpha-smooth muscle actin (alpha-SMA) in capillary pericytes.