Biochemical markers of bone turnover in the diagnosis of renal osteodystrophy in dialyzed children

Baskin E., Besbas N., Saatci U., Hascelik G., Topaloglu R., Ozen S., ...Daha Fazla

TURKISH JOURNAL OF PEDIATRICS, cilt.46, sa.1, ss.28-31, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 1
  • Basım Tarihi: 2004
  • Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.28-31
  • Hacettepe Üniversitesi Adresli: Evet

Özet

In this study we investigated the value of biochemical markers of bone turnover in the diagnosis of renal osteodystrophy in dialysis patients. The study was carried out in 22 chronic renal failure patients (mean age: 16.1+/-4.5) being treated with chronic dialysis. There were three groups according to intact parathormone (iPTH) levels: Group I (n: 6): iPTH levels were less than 200 pg/ml; Group II (n: 9): iPTH levels were between 201 and 500 pg/ml; and Group III (n: 7). iPTH levels were higher than 501 pg/ml. We investigated iPTH, bone alkaline phosphatase, total serum alkaline phosphatase, osteocalcin, serum type I procollagen peptide (PICP) and insulin-like growth factor-1 (IGF-1) levels in all patients.