Synthesis and characterization of monodisperse-porous, zwitterionic microbeads

KİBAR G. , Tuncel A.

POLYMER BULLETIN, cilt.73, ss.1939-1950, 2016 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 73 Konu: 7
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s00289-015-1586-y
  • Sayfa Sayıları: ss.1939-1950


Zwitterionic, monodisperse-porous polymer beads were newly synthesized using a hydrophilic acrylic crosslinker (glycerol dimethacrylate, GDMA) or a hydrophobic one (ethylene dimethacrylate) including a zwitterionic functional monomer sulfopropyl-2-vinylpyridinium hydroxide (SVP) in a modified-staged shape template polymerization. The effects of monomer/seed latex ratio and diluent/seed latex ratio on the particle size, mean pore size, pore size distribution and specific surface area of the poly(1-(3-sulfopropyl)-2-vinylpyridinium hydroxide-co-glycerol dimethacrylate) poly(SVP-co-GDMA) and poly(1-(3-sulfopropyl)-2-vinylpyridinium hydroxide-co-ethylene glycerol dimethacrylate) poly(SVP-co-EDMA) microbeads were investigated. For both types of microbeads, the mean size decreased with decreasing monomer/seed latex ratio and decreasing diluent/seed latex ratio. Almost tenfold higher specific surface area was achieved using a hydrophobic crosslinking agent (EDMA) with respect to the hydrophilic one. Poly(SVP-co-GDMA) microbeads were satisfactorily used as a stationary phase in HILIC mode for the isocratic separation of polar organics with the plate heights up to 124 microns.