An audit analysis of a guideline for the investigation and initial therapy of diarrhea negative (atypical) hemolytic uremic syndrome


Johnson S., Stojanovic J., Ariceta G., Bitzan M., BEŞBAŞ N. , Frieling M., ...More

PEDIATRIC NEPHROLOGY, vol.29, no.10, pp.1967-1978, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 10
  • Publication Date: 2014
  • Doi Number: 10.1007/s00467-014-2817-4
  • Title of Journal : PEDIATRIC NEPHROLOGY
  • Page Numbers: pp.1967-1978

Abstract

In 2009, the European Paediatric Study Group for Haemolytic Uraemic Syndrome (HUS) published a clinical practice guideline for the investigation and initial therapy of diarrhea-negative HUS (now more widely referred to as atypical HUS, aHUS). The therapeutic component of the guideline (comprising early, high-volume plasmapheresis) was derived from anecdotal evidence and expert consensus, and the authors committed to auditing outcome.