An audit analysis of a guideline for the investigation and initial therapy of diarrhea negative (atypical) hemolytic uremic syndrome

Johnson, Sally; Stojanovic, Jelena; Ariceta, Gema; Bitzan, Martin; BEŞBAŞ, NESRİN; Frieling, Michelle; Karpman, Diana; Landau, Daniel; Langman, Craig; Licht, Christoph; Pecoraro, Carmine; Riedl, Magdalena; Siomou, Ekaterini; van de Kar, Nicole; Vande Walle, Johan; Loirat, Chantal; Taylor, C.

doi:10.1007/s00467-014-2817-4

An audit analysis of a guideline for the investigation and initial therapy of diarrhea negative (atypical) hemolytic uremic syndrome

Johnson S., Stojanovic J., Ariceta G., Bitzan M., BEŞBAŞ N., Frieling M., ...More

PEDIATRIC NEPHROLOGY, vol.29, no.10, pp.1967-1978, 2014 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 29 Issue: 10
Publication Date: 2014
Doi Number: 10.1007/s00467-014-2817-4
Journal Name: PEDIATRIC NEPHROLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1967-1978
Hacettepe University Affiliated: Yes

Abstract

In 2009, the European Paediatric Study Group for Haemolytic Uraemic Syndrome (HUS) published a clinical practice guideline for the investigation and initial therapy of diarrhea-negative HUS (now more widely referred to as atypical HUS, aHUS). The therapeutic component of the guideline (comprising early, high-volume plasmapheresis) was derived from anecdotal evidence and expert consensus, and the authors committed to auditing outcome.