In the current study, it was aimed to investigate the relationship of organizational cynicism and burnout of the academicians' work in state universities. A total of 392 academicians working in different faculties of four state universities located in Ankara participated in the study. The data collection tools were "Organizational Cynicism Scale" developed by Brandes, Dharwadkar, and Dean (1999), and "Maslach Burnout Inventory" developed by Maslach and Jackson (1981). The data were analyzed by conducting t test, ANOVA, Pearson correlation and multiple linear regression. The construct validity of the scales used within the study was tested by confirmatory factor analysis, and as for the internal reliability, Cronbach alpha values were calculated. The Cronbach alpha value of the Organizational Cynicism Scale was calculated as.93, the Cronbach alpha value of emotional exhaustion, depersonalization and personal accomplishment sub-dimensions of Maslach Burnout Inventory were calculated sequentially as .88, .74 and .73. In the study, it was found that academicians had moderate levels of organizational cynicism, and low levels of burnout. The study also showed that there was a moderate, positive and statistically significant relationship between academicians' organizational cynicism attitudes and emotional exhaustion and depersonalization sub-dimensions of burnout, and there was no statistically significant relationship between academicians' organizational cynicism attitudes and personal accomplishment sub-dimension of burnout. In addition, it was concluded that organizational cynicism was a significant predictor of emotional exhaustion and depersonalization sub-dimensions of burnout.