Circulating Epstein-Barr virus DNA and cell-free DNA in pediatric lymphomas

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YALÇIN B., Kutluk T., Agbaba S. K., Demir C., TALİM B.

TURKISH JOURNAL OF PEDIATRICS, vol.62, no.4, pp.541-550, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 62 Issue: 4
  • Publication Date: 2020
  • Doi Number: 10.24953/turkjped.2020.04.003
  • Journal Name: TURKISH JOURNAL OF PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.541-550
  • Keywords: Hodgkin lymphoma, non-Hodgkin lymphoma, serum Epstein-Barr virus, serum cell-free DNA, children, EBV-DNA, HODGKIN-DISEASE, PLASMA, CHILDREN, BIOMARKER, QUANTIFICATION, SERUM
  • Hacettepe University Affiliated: Yes

Abstract

Background and objectives. Quantification of serum Epstein-Barr virus (EBV) DNA and/or cell-free total DNA (cf-DNA) may become valuable sources for prognosis evaluation and monitoring treatment response in lymphomas. We aimed to investigate their roles as potential markers in pediatric Hodgkin (HL) and non-Hodgkin lymphomas (NHL).