Cycloartane triterpene glycosides from the roots of <i>Astragalus brachypterus </i>and <i>Astragalus microcephalus </i>
JOURNAL OF NATURAL PRODUCTS, no.12, pp.1469-1472, 1998 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Publication Date: 1998
- Doi Number: 10.1021/np9801763
- Journal Name: JOURNAL OF NATURAL PRODUCTS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
- Page Numbers: pp.1469-1472
- Hacettepe University Affiliated: Yes
Abstract
Three new cycloartane-type triterpene glycosides, brachyosides A (1), B (3), and C (2), from the roots of Astragalus brachypterus and one new glycoside, cyclocephaloside II (4), from the roots of Astragalus microcephalus have been isolated together with five known saponins, astragalosides I, II, and IV, cyclocanthoside E, and cycloastragenol. The structures of the new compounds were established as 3-O-[beta-D-xylopyranosyl(1-->3)-beta-D-xylopyranosyl-3 beta,6 alpha,24(S),25-pentahydroxycycloartane (1), 3-O-beta-D-xylopyranosyl-6-O-beta-D-glucopyran pentahydroxycycloartane (2), 20(R),24(S)-epoxy-6-O-beta-glucopyranosyl-3 (3), and 20(R),24(S)-epoxy-3-O-(4'-O-acetyl)-beta-D-16 beta,25-tetrahydroxycycloartane (4). For the structure elucidations, 1D- and 2D-NMR experiments and FABMS were used.