Cycloartane triterpene glycosides from the roots of <i>Astragalus brachypterus </i>and <i>Astragalus microcephalus </i>
JOURNAL OF NATURAL PRODUCTS, sa.12, ss.1469-1472, 1998 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Basım Tarihi: 1998
- Doi Numarası: 10.1021/np9801763
- Dergi Adı: JOURNAL OF NATURAL PRODUCTS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
- Sayfa Sayıları: ss.1469-1472
- Hacettepe Üniversitesi Adresli: Evet
Özet
Three new cycloartane-type triterpene glycosides, brachyosides A (1), B (3), and C (2), from the roots of Astragalus brachypterus and one new glycoside, cyclocephaloside II (4), from the roots of Astragalus microcephalus have been isolated together with five known saponins, astragalosides I, II, and IV, cyclocanthoside E, and cycloastragenol. The structures of the new compounds were established as 3-O-[beta-D-xylopyranosyl(1-->3)-beta-D-xylopyranosyl-3 beta,6 alpha,24(S),25-pentahydroxycycloartane (1), 3-O-beta-D-xylopyranosyl-6-O-beta-D-glucopyran pentahydroxycycloartane (2), 20(R),24(S)-epoxy-6-O-beta-glucopyranosyl-3 (3), and 20(R),24(S)-epoxy-3-O-(4'-O-acetyl)-beta-D-16 beta,25-tetrahydroxycycloartane (4). For the structure elucidations, 1D- and 2D-NMR experiments and FABMS were used.