Formulation and characterization of liquid crystal systems containing azelaic acid for topical delivery

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AYTEKİN M., GÜRSOY R. N., İDE S., SOYLU E. H., HEKİMOĞLU S.

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, vol.39, no.2, pp.228-239, 2013 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 39 Issue: 2
• Publication Date: 2013
• Doi Number: 10.3109/03639045.2012.671829
• Journal Name: DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.228-239
• Keywords: lamellar liquid crystals, skin interaction, azelaic acid, in vitro release, SAXS, DSC, HUMAN STRATUM-CORNEUM, HUMAN SKIN, PERMEATION, MICROSTRUCTURE, MICROEMULSIONS, SURFACTANT, RHEOLOGY, BEHAVIOR, RELEASE, PHASE
• Hacettepe University Affiliated: Yes

Abstract

Purpose: The aim of this study is to prepare and characterize azelaic acid (AzA) containing liquid crystal (LC) drug delivery systems for topical use.