IL1RN Variation Influences Both Disease Susceptibility and Response to Recombinant Human Interleukin-1 Receptor Antagonist Therapy in Systemic Juvenile Idiopathic Arthritis

Arthur, Victoria; Shuldiner, Emily; Remmers, Elaine; Hinks, Anne; Grom, Alexei; Foell, Dirk; Martini, Alberto; Gattorno, Marco; ÖZEN, SEZA; Prahalad, Sampath; Zeft, Andrew; Bohnsack, John; Ilowite, Norman; Mellins, Elizabeth; Russo, Ricardo; Len, Claudio; Oliveira, Sheila; Yeung, Rae; Rosenberg, Alan; Wedderburn, Lucy; Anton, Jordi; Haas, Johannes-Peter; Roesen-Wolff, Angela; Minden, Kirsten; Szymanski, Ann; Thomson, Wendy; Kastner, Daniel; Woo, Patricia; Ombrello, Michael

doi:10.1002/art.40498

IL1RN Variation Influences Both Disease Susceptibility and Response to Recombinant Human Interleukin-1 Receptor Antagonist Therapy in Systemic Juvenile Idiopathic Arthritis

Atıf İçin Kopyala

Arthur V. L. , Shuldiner E., Remmers E. F. , Hinks A., Grom A. A. , Foell D., ...Daha Fazla

ARTHRITIS & RHEUMATOLOGY, cilt.70, ss.1319-1330, 2018 (SCI İndekslerine Giren Dergi)

Cilt numarası: 70 Konu: 8
Basım Tarihi: 2018
Doi Numarası: 10.1002/art.40498
Dergi Adı: ARTHRITIS & RHEUMATOLOGY
Sayfa Sayıları: ss.1319-1330

Özet

Objective. To determine whether systemic juvenile idiopathic arthritis (JIA) susceptibility loci that were identified by candidate gene studies demonstrate association with systemic JIA in the largest study population assembled to date.