Value of serum and induced sputum surfactant protein-D in chronic obstructive pulmonary disease


Ozyurek B. A. , Ulasli S. , Bozbas S. S. , Bayraktar N., Akcay S.

MULTIDISCIPLINARY RESPIRATORY MEDICINE, vol.8, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8
  • Publication Date: 2013
  • Doi Number: 10.1186/2049-6958-8-36
  • Title of Journal : MULTIDISCIPLINARY RESPIRATORY MEDICINE

Abstract

Background: Surfactant Protein D (SP-D) is an important marker in chronic obstructive pulmonary disease (COPD). Serum SP-D levels increase while lung production of SP-D decreases in COPD. SP-D is a specific biomarker for monitoring COPD, assessment of exacerbation frequency and arrangement of treatment modalities. In the present study, we aimed to investigate the correlation between serum and induced sputum SP-D levels with severity and acute exacerbations of COPD.