Evaluation of c-Met, HGF, and HER-2 expressions in gastric carcinoma and their association with other clinicopathological factors

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Yildiz Y., SÖKMENSÜER C., YALÇIN Ş.

ONCOTARGETS AND THERAPY, cilt.9, ss.5809-5817, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9
  • Basım Tarihi: 2016
  • Doi Numarası: 10.2147/ott.s107946
  • Dergi Adı: ONCOTARGETS AND THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.5809-5817
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Met and HER-2 are proto-oncogenes encoding receptor tyrosine kinase c-Met and HER-2, respectively. Hepatocyte growth factor (HGF) is a ligand of c-Met. The frequency of c-Met, HGF, and HER-2 expressions in gastric cancer and their association with other clinicopathological factors have not been fully understood.