In the present study, the effects of mold temperature, superheat, mold thickness, and Mg2Si amount on the fluidity of the Al-Mg2Si as-cast in-situ composites were investigated using the mathematical models. Composites with different amounts of Mg2Si were fabricated, and the fluidity and microstructure of each were then analyzed. For this purpose, the experiments were designed using a central composite rotatable design, and the relationship between parameters and fluidity were developed using the response surface method. In addition, optical and scanning electron microscopes were used for microstructural observation. The ANOVA shows that the mathematical models can predict the fluidity accurately. The results show that by increasing the mold temperature from 25 degrees C to 200 degrees C, superheat from 50 degrees C to 250 degrees C, and thickness from 3 mm to 12 mm, the fluidity of the composites decreases, where the mold thickness is more effective than other factors. In addition, the higher amounts of Mg2Si in the range from 15wt.% to 25wt.% lead to the lower fluidity of the composites. For example, when the mold temperature, superheat, and thickness are respectively 100 degrees C, 150 degrees C, and 7 mm, the fluidity length is changed in the range of 11.9 cm to 15.3 cm. By increasing the amount of Mg2Si, the morphology of the primary Mg2Si becomes irregular and the size of primary Mg2Si is increased. Moreover, the change of solidification mode from skin to pasty mode is the most noticeable microstructural effect on the fluidity.