Regioselective addition of pyrrole to N-tosyl imines in the presence of Cu(OTf)(2)

Temelli B. , Unaleroglu C.

TETRAHEDRON LETTERS, vol.46, no.46, pp.7941-7943, 2005 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 46
  • Publication Date: 2005
  • Doi Number: 10.1016/j.tetlet.2005.09.090
  • Title of Journal : TETRAHEDRON LETTERS
  • Page Numbers: pp.7941-7943


The Cu(OTf)(2) catalysed reaction of pyrrole with N-tosyl imines gives pyrrole sulfonamides in high yields. The addition reaction takes place regioselectively at C(2) of the pyrrole. The procedure is simple and does not require anhydrous conditions. (c) 2005 Elsevier Ltd. All rights reserved.