Lamotrigine augmentation in patients with schizophrenia who show partial response to clozapine treatment


Vayisoglu S., Yagcioglu A. E. A. , Yagcioglu S. , KARAHAN S. , Karci O., GÜREL Ş. C. , ...Daha Fazla

SCHIZOPHRENIA RESEARCH, cilt.143, sa.1, ss.207-214, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 143 Konu: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.schres.2012.11.006
  • Dergi Adı: SCHIZOPHRENIA RESEARCH
  • Sayfa Sayıları: ss.207-214

Özet

Background: Several placebo controlled studies investigating lamotrigine augmentation of clozapine in schizophrenia patients with partial response have shown varying results. The aim of this study was to further investigate the efficacy and safety of this augmentation strategy, and its effect on the glutamatergic system through utilizing mismatch negativity (MMN) component of auditory event related potentials.