Lamotrigine augmentation in patients with schizophrenia who show partial response to clozapine treatment


Vayisoglu S., Yagcioglu A. E. A. , Yagcioglu S. , KARAHAN S. , Karci O., GÜREL Ş. C. , ...More

SCHIZOPHRENIA RESEARCH, vol.143, no.1, pp.207-214, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 143 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.1016/j.schres.2012.11.006
  • Title of Journal : SCHIZOPHRENIA RESEARCH
  • Page Numbers: pp.207-214

Abstract

Background: Several placebo controlled studies investigating lamotrigine augmentation of clozapine in schizophrenia patients with partial response have shown varying results. The aim of this study was to further investigate the efficacy and safety of this augmentation strategy, and its effect on the glutamatergic system through utilizing mismatch negativity (MMN) component of auditory event related potentials.