SCHIZOPHRENIA RESEARCH, vol.143, no.1, pp.207-214, 2013 (Journal Indexed in SCI)
Article / Article
Title of Journal :
Schizophrenia, Clozapine, Augmentation, Lamotrigine, Mismatch negativity, EVENT-RELATED POTENTIALS, MISMATCH NEGATIVITY, DOUBLE-BLIND, RESISTANT SCHIZOPHRENIA, GLUTAMATE SYSTEM, RISPERIDONE, RELEVANCE, KETAMINE, EFFICACY, MEMORY
Background: Several placebo controlled studies investigating lamotrigine augmentation of clozapine in schizophrenia patients with partial response have shown varying results. The aim of this study was to further investigate the efficacy and safety of this augmentation strategy, and its effect on the glutamatergic system through utilizing mismatch negativity (MMN) component of auditory event related potentials.