Insight into the fabrication, characterization, and in vitro cytotoxicity studies approaches of halloysite-based functional anhydride containing polymer nanocomposites

Aydin K., Sevim Akan H., Kaplan Can H.

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, cilt.73, sa.1, ss.79-90, 2024 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 73 Sayı: 1
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1080/00914037.2022.2124254
  • Dergi Adı: INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chemical Abstracts Core, Chimica, Compendex, INSPEC
  • Sayfa Sayıları: ss.79-90
  • Anahtar Kelimeler: Copolymer, halloysite, human gingival fibroblasts, nanocomposite, nanotube, poly(MA-alt-VA), XPS, MALEIC-ANHYDRIDE, CLAY NANOTUBES, MONTMORILLONITE, TEMPERATURE, DERIVATIVES, DOXORUBICIN, COPOLYMERS, STRENGTH
  • Hacettepe Üniversitesi Adresli: Evet

Özet

This study aims to design, synthesize, and characterization of maleic anhydride-vinyl acetate and its halloysite nanotubes and to evaluate the cytotoxic effects of nanostructures on human gingival fibroblasts. Poly(maleic anhydride-alt-vinyl acetate) [Poly(MA-alt-VA)] was synthesized via charge transfer complex-radical polymerization as potential dental fillings, adhesives, or bone cement materials. ATR-FTIR, XPS, and XRD spectroscopic methods were used to enlighten the structure-property of nanomaterials. Determining surface area and pore volume BET was used. Morphological characterization was viewed by HRTEM. Cytotoxic effects of nanocomposites on cell viability were evaluated by MTT assay for different incubation periods and concentrations for human gingival fibroblasts.