Participation of Lower and Upper Middle-Income Countries in Clinical Trials Led by High-Income Countries

Rubagumya, Fidel; Hopman, Wilma; Gyawali, Bishal; Mukherji, Deborah; Hammad, Nazik; Pramesh, C.; Zubaryev, Mykola; Eniu, Alexandru; Tsunoda, Audrey; Kutluk, Tezer; Aggarwal, Ajay; Sullivan, Richard; Booth, Christopher

doi:10.1001/jamanetworkopen.2022.27252

Participation of Lower and Upper Middle-Income Countries in Clinical Trials Led by High-Income Countries

Rubagumya F., Hopman W. M., Gyawali B., Mukherji D., Hammad N., Pramesh C. S., ...More

JAMA NETWORK OPEN, vol.5, no.8, 2022 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 5 Issue: 8
Publication Date: 2022
Doi Number: 10.1001/jamanetworkopen.2022.27252
Journal Name: JAMA NETWORK OPEN
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, Directory of Open Access Journals
Open Archive Collection: AVESIS Open Access Collection
Hacettepe University Affiliated: Yes

Abstract

IMPORTANCE Many randomized clinical trials (RCTs) led by high-income countries (HICs) now enroll patients from lower middle-income countries (LMICs) and upper middle-income countries (UMICs). Although enrolling diverse populations promotes research collaborations, there are issues regarding which countries participate in RCTs and how this participation may contribute to global research.