Participation of Lower and Upper Middle-Income Countries in Clinical Trials Led by High-Income Countries

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Rubagumya F., Hopman W. M., Gyawali B., Mukherji D., Hammad N., Pramesh C. S., ...More

JAMA NETWORK OPEN, vol.5, no.8, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 8
  • Publication Date: 2022
  • Doi Number: 10.1001/jamanetworkopen.2022.27252
  • Journal Name: JAMA NETWORK OPEN
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, Directory of Open Access Journals
  • Hacettepe University Affiliated: Yes


IMPORTANCE Many randomized clinical trials (RCTs) led by high-income countries (HICs) now enroll patients from lower middle-income countries (LMICs) and upper middle-income countries (UMICs). Although enrolling diverse populations promotes research collaborations, there are issues regarding which countries participate in RCTs and how this participation may contribute to global research.