Non-Invasive Separation of Alcoholic and Non-Alcoholic Liver Disease with Predictive Modeling


Sowa J., Atmaca O. , Kahraman A., Schlattjan M., Lindner M., Sydor S., ...Daha Fazla

PLOS ONE, cilt.9, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Background & Objective: Currently, a major clinical challenge is to distinguish between chronic liver disease caused by metabolic syndrome (non-alcoholic fatty liver disease, NAFLD) from that caused by long term or excessive alcohol consumption (ALD). The etiology of severe liver disease affects treatment options and priorities for liver transplantation and organ allocation. Thus we compared physiologically similar NAFLD and ALD patients to detect biochemical differences for improved separation of these mechanistically overlapping etiologies.