Evaluation of thyroid function tests of acne vulgaris patients treated with systemic isotretinoin

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Yildirim N., Dogan S., Atakan N.

JOURNAL OF DERMATOLOGICAL TREATMENT, vol.28, no.2, pp.141-144, 2017 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 28 Issue: 2
• Publication Date: 2017
• Doi Number: 10.1080/09546634.2016.1214232
• Journal Name: JOURNAL OF DERMATOLOGICAL TREATMENT
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.141-144
• Hacettepe University Affiliated: Yes

Abstract

Background: Isotretinoin is a systemic retinoid used to treat acne and it binds receptors which are the member of steroid-thyroid hormone superfamily. Certain types of retinoids may cause abnormalities in serum thyroid function tests (sTFTs) by suppressing thyroid stimulating hormone (TSH). However, it is uncertain whether systemic isotretinoin has any effect on sTFTs.Objective: The aim of the study was to find out if there is any alteration in sTFTs of patients with acne vulgaris treated with systemic isotretinoin.