Evaluation of thyroid function tests of acne vulgaris patients treated with systemic isotretinoin

Yildirim N., Dogan S., Atakan N.

JOURNAL OF DERMATOLOGICAL TREATMENT, vol.28, no.2, pp.141-144, 2017 (SCI-Expanded) identifier identifier identifier


Background: Isotretinoin is a systemic retinoid used to treat acne and it binds receptors which are the member of steroid-thyroid hormone superfamily. Certain types of retinoids may cause abnormalities in serum thyroid function tests (sTFTs) by suppressing thyroid stimulating hormone (TSH). However, it is uncertain whether systemic isotretinoin has any effect on sTFTs.Objective: The aim of the study was to find out if there is any alteration in sTFTs of patients with acne vulgaris treated with systemic isotretinoin.