Enhanced oral absorption of paclitaxel in a novel self-microemulsifying drug delivery system with or without concomitant use of P-glycoprotein inhibitors

Yang, SC; Gursoy, RN; Lambert, G; Benita, S

doi:10.1023/b:pham.0000016238.44452.f1

Enhanced oral absorption of paclitaxel in a novel self-microemulsifying drug delivery system with or without concomitant use of P-glycoprotein inhibitors

Yang S., Gursoy R., Lambert G., Benita S.

PHARMACEUTICAL RESEARCH, cilt.21, sa.2, ss.261-270, 2004 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 21 Sayı: 2
Basım Tarihi: 2004
Doi Numarası: 10.1023/b:pham.0000016238.44452.f1
Dergi Adı: PHARMACEUTICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.261-270
Hacettepe Üniversitesi Adresli: Hayır

Özet

Purpose. The objective of this study was to evaluate the pharmacokinetics of paclitaxel in a novel self-microemulsifying drug delivery system (SMEDDS) for improved oral administration with or without P-glycoprotein (P-gp) inhibitors.