Enhanced oral absorption of paclitaxel in a novel self-microemulsifying drug delivery system with or without concomitant use of P-glycoprotein inhibitors


Yang S., Gursoy R., Lambert G., Benita S.

PHARMACEUTICAL RESEARCH, cilt.21, ss.261-270, 2004 (SCI İndekslerine Giren Dergi) identifier identifier

Özet

Purpose. The objective of this study was to evaluate the pharmacokinetics of paclitaxel in a novel self-microemulsifying drug delivery system (SMEDDS) for improved oral administration with or without P-glycoprotein (P-gp) inhibitors.