Evaluation of the Effect of Proanthocyanidin in Experimental Cerebral Vasospasm: Electron microscopically and by Biochemical Stress Parameters

Tekiner A., Sargon M. F., Bayar M. A., Yucel D., Senes M., Caner H.

Neurotrauma and Vascular Neurosurgery Joint EANS Annual Meeting / 4th World ICH Conference, Newcastle, Australia, 2 - 05 May 2011, pp.81-85 identifier

  • Publication Type: Conference Paper / Full Text
  • Volume:
  • City: Newcastle
  • Country: Australia
  • Page Numbers: pp.81-85
  • Hacettepe University Affiliated: Yes


Cerebral vasospasm is an important cause of morbidity and mortality following subarachnoid hemorrhage (SAH). Oxygen free radical generation is increased after SAH and that these radicals and consequently lipid peroxidation may be causally related to the expression of cerebral vasospasm. In this experimental study, SAH model was performed to the rabbits basilar artery and cerebral cortex were examined by electron microscope and oxidative/nitrosative stress parameters.