Bacterial cellulose micro-nano fibres for wound healing applications

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Ahmed J., Gultekinoglu M., Edirisinghe M.

BIOTECHNOLOGY ADVANCES, cilt.41, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 41
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.biotechadv.2020.107549
  • Dergi Adı: BIOTECHNOLOGY ADVANCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aerospace Database, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Communication Abstracts, Compendex, EMBASE, Environment Index, Geobase, INSPEC, MEDLINE, Metadex, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
  • Anahtar Kelimeler: Bacterial cellulose, Wound healing, Fibres, Gluconacetobacter xylinum, Fibre production, SUPER-HYDROPHOBIC SURFACES, DRUG-DELIVERY SYSTEMS, NATA-DE-COCO, MECHANICAL-PROPERTIES, ACETOBACTER-XYLINUM, ELASTIC-MODULUS, IN-VITRO, MEMBRANES, CULTURE, WATER
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Bacterial cellulose (BC) is cellulose produced by a few limited species of bacteria in given conditions. BC has many remarkable properties such as its attractive mechanical properties, water uptake ability and biocompatibility which makes it a very desirable material to be used for wound healing. Inherently due to these important properties, the material is very resistant to easy processing and thus difficult to produce into useful entities. Additionally, being rate limited by the dependency on bacterial production, high yield is difficult to obtain and thus secondary material processing is sought after. In this review, BC is explained in terms of synthesis, structure and properties. These beneficial properties are directly related to the material's great potential in wound healing where it has also been trialled commercially but ultimately failed due to processing issues. However, more recently there has been increased frequency in scientific work relating to BC processing into hybrid polymeric fibres using common laboratory fibre forming techniques such as electrospinning and pressurised gyration. This paper summarises current progress in BC fibre manufacturing, its downfalls and also gives a future perspective on how the landscape should change to allow BC to be utilised in wound care in the current environment.