Treatment Response and Outcome with Two Different Prednisolone Regimens in Autoimmune Hepatitis

PÜRNAK T., Efe C., KAV T., Wahlin S., Ozaslan E.

DIGESTIVE DISEASES AND SCIENCES, vol.62, no.10, pp.2900-2907, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 62 Issue: 10
  • Publication Date: 2017
  • Doi Number: 10.1007/s10620-017-4728-2
  • Journal Name: DIGESTIVE DISEASES AND SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2900-2907
  • Hacettepe University Affiliated: Yes

Abstract

Beyond available guidelines, therapy of autoimmune hepatitis (AIH) shows wide variation among physicians. We compared two regimens for treatment naive AIH: one recommended protocol with an initial prednisolone dose of 30 mg/day and our own 40 mg/day prednisolone with a slow dose tapering protocol. We analyzed the safety, response rates, and outcomes for two groups of treated patients.