Sleep disordered breathing in patients with Prader willi syndrome: Impact of underlying genetic mechanism

Ozsezen B., EMİRALİOĞLU N., Ozon A., Akin O., Tural D. A., SUNMAN B., ...More

RESPIRATORY MEDICINE, vol.187, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 187
  • Publication Date: 2021
  • Doi Number: 10.1016/j.rmed.2021.106567
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Pollution Abstracts
  • Keywords: Prader willi syndrome, Sleep disordered breathing, Central sleep apnea, Apnea-hypopnea index, Growth hormone, GROWTH-HORMONE TREATMENT, PULMONARY-FUNCTION, CHILDREN, BEHAVIOR, APNEA, CHROMOSOME-15, QUESTIONNAIRE, PREVALENCE, PREDICTION, COGNITION
  • Hacettepe University Affiliated: Yes


Introduction: Sleep-disordered breathing (SDB) is common in children with PWS. In the current study, we aimed to evaluate the severity of SDB in patients with PWS using polysomnography (PSG), and assess the effect of the underlying genetic mechanism on PSG parameters.