Sleep disordered breathing in patients with Prader willi syndrome: Impact of underlying genetic mechanism


Ozsezen B., EMİRALİOĞLU N. , Ozon A. , Akin O., Tural D. A. , SUNMAN B. , ...More

RESPIRATORY MEDICINE, vol.187, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 187
  • Publication Date: 2021
  • Doi Number: 10.1016/j.rmed.2021.106567
  • Title of Journal : RESPIRATORY MEDICINE
  • Keywords: Prader willi syndrome, Sleep disordered breathing, Central sleep apnea, Apnea-hypopnea index, Growth hormone, GROWTH-HORMONE TREATMENT, PULMONARY-FUNCTION, CHILDREN, BEHAVIOR, APNEA, CHROMOSOME-15, QUESTIONNAIRE, PREVALENCE, PREDICTION, COGNITION

Abstract

Introduction: Sleep-disordered breathing (SDB) is common in children with PWS. In the current study, we aimed to evaluate the severity of SDB in patients with PWS using polysomnography (PSG), and assess the effect of the underlying genetic mechanism on PSG parameters.