Treatment of acromegaly by endoscopic transsphenoidal surgery: surgical experience in 214 cases and cure rates according to current consensus criteria


Hazer D. B. , Isik S., Berker D., Guler S., Gurlek A., Yucel T., ...Daha Fazla

JOURNAL OF NEUROSURGERY, cilt.119, ss.1467-1477, 2013 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 119 Konu: 6
  • Basım Tarihi: 2013
  • Doi Numarası: 10.3171/2013.8.jns13224
  • Dergi Adı: JOURNAL OF NEUROSURGERY
  • Sayfa Sayıları: ss.1467-1477

Özet

Object. Acromegaly is a disease that has significant morbidity and mortality related to high levels of growth hormone (GH) and insulin-like growth factor I (IGF-I), and is usually caused by pituitary adenomas. The goal in this study was to investigate the role of endoscopic transsphenoidal surgery and surgical experience in the treatment of OH adenoma cases in relation to surgical results and hormonal cure rates, and to perform a review of the literature.