Treatment of acromegaly by endoscopic transsphenoidal surgery: surgical experience in 214 cases and cure rates according to current consensus criteria


Hazer D. B. , Isik S., Berker D., Guler S., Gurlek A., Yucel T., ...More

JOURNAL OF NEUROSURGERY, vol.119, no.6, pp.1467-1477, 2013 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 119 Issue: 6
  • Publication Date: 2013
  • Doi Number: 10.3171/2013.8.jns13224
  • Title of Journal : JOURNAL OF NEUROSURGERY
  • Page Numbers: pp.1467-1477

Abstract

Object. Acromegaly is a disease that has significant morbidity and mortality related to high levels of growth hormone (GH) and insulin-like growth factor I (IGF-I), and is usually caused by pituitary adenomas. The goal in this study was to investigate the role of endoscopic transsphenoidal surgery and surgical experience in the treatment of OH adenoma cases in relation to surgical results and hormonal cure rates, and to perform a review of the literature.