Treatment of acromegaly by endoscopic transsphenoidal surgery: surgical experience in 214 cases and cure rates according to current consensus criteria

Hazer D. B., Isik S., Berker D., Guler S., Gurlek A., Yucel T., ...Daha Fazla

JOURNAL OF NEUROSURGERY, cilt.119, sa.6, ss.1467-1477, 2013 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 119 Sayı: 6
  • Basım Tarihi: 2013
  • Doi Numarası: 10.3171/2013.8.jns13224
  • Dergi Adı: JOURNAL OF NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1467-1477
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Object. Acromegaly is a disease that has significant morbidity and mortality related to high levels of growth hormone (GH) and insulin-like growth factor I (IGF-I), and is usually caused by pituitary adenomas. The goal in this study was to investigate the role of endoscopic transsphenoidal surgery and surgical experience in the treatment of OH adenoma cases in relation to surgical results and hormonal cure rates, and to perform a review of the literature.